ceesdekker.net Fundamentals Explained
ceesdekker.net Fundamentals Explained
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You frequently get involved in conversations about science and faith. You may have also composed several textbooks on the subject. Don’t you are convinced at some time We're going to know almost everything and that God’s job will likely be over?
Dynamics of initiation, termination and reinitiation of DNA translocation because of the motor protein EcoR124I
Considering that 2000, Dekker has shifted the main emphasis of his do the job in the direction of biophysics the place he studies the Qualities of solitary biomolecules and cells utilizing the tools of nanotechnology. This variation of subject was pushed by his fascination for your impressive operating of Organic molecular structures, along with with the extensive-term perspective that lots of exciting discoveries is usually envisioned in this area.[5] Existing traces of investigation in his biophysics team are from the parts of:[six]
2015, discovery that condensin is a really versatile protein structure; and to start with detection of DNA knots employing nanopores
Case in point (3) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in grey, the rim of the pore is highlighted in purple, as well as a 3D rendering from the motion with the DNA rod is shown.
Length control of individual carbon nanotubes by nanostructuring with the scanning tunneling microscope
Instance (one) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim with the pore is highlighted in crimson, in addition to a 3D rendering in the movement in the DNA rod is displayed.
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Dekker started off his investigation on single carbon nanotubes in 1993 when he set up a new line of investigate to review electrical transport as a result of solitary natural molecules between nanoelectrodes. In 1996 a breakthrough was recognized with carbon nanotubes. This was attained in a collaboration Along with the group of Nobel laureate Richard Smalley. STM and nanolithography techniques cees dekker ended up used to reveal that these nanotubes are quantum wires at The only-molecule amount, with fantastic physical Houses.
Due to the fact 2000 he moved to single-molecule biophysics and nanobiology, with exploration from research of DNA loop extrusion and supercoiling to DNA translocation by nanopores. Much more a short while ago his analysis has centered on studying chromatin construction and mobile division with bacteria on chip, although he is usually attempting to eventually Establish synthetic cells from the bottom up.
Cees Dekker is Distinguished College Professor at TU Delft. Properly trained to be a physicist, he pioneered nanotechnology with many discoveries on carbon nanotubes within the 1990s. Given that 2000, he moved to single-molecule biophysics and nanobiology. His present analysis focuses on (i) nanopores for protein sequencing; (ii) chromosome construction, in particular SMC motor protein; and (iii) building a dwelling artificial mobile from lifeless molecules. Dekker is undoubtedly an elected member with the KNAW and fellow to your APS plus the IOP.
2008, initial observation of protein-coated DNA translocation by means of nanopores; settled the origin in the electrophoretic power on DNA in nanopores; found a substantial velocity boost of microtubules in electric fields; found an anomalous electro-hydrodynamic orientation of microtubules; and resolved the origin of noise in carbon nanotubes in liquid
2004, discovery of new physics in translocation of DNA through nanopores; initially experimental research of ions conduction in nanofluidic channels; first electrochemistry with particular person single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; initial electrical docking of microtubules on kinesin-coated nanostructures; initially biophysics characterization in the mechanical Attributes of double-stranded RNA; and very first one-molecule research of DNA translocation by a restriction-modification enzyme.